Famous Opioids Withdrawal Symptoms References. People may recognize symptoms of withdrawal when they stop taking or cut back on a substance. Sweating or hot and cold flushes muscle, bone and joint aches and pains or muscle cramps nausea, diarrhoea or abdominal cramps headache s insomnia anxiety or agitation rapid heart rate ( tachycardia)

Runny nose watery eyes yawning sweating fever muscle pain bone pain joint pain stomach cramping and pain vomiting and nausea goosebumps appetite loss high blood pressure elevated heart rate irritability agitation anxiety Untreated opioid withdrawal frequently results in return to opioid use. Many people also experience anxiety and agitation.